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  1. Particulate matter 2.5 (PM2.5) deposition in the lung’s alveolar capillary region (ACR) is significantly associated with respiratory disease development, yet the molecular mechanisms are not completely understood...

    Authors: Eva C. M. Vitucci, Alysha E. Simmons, Elizabeth M. Martin and Shaun D. McCullough
    Citation: Particle and Fibre Toxicology 2024 21:15
  2. Wildland fires contribute significantly to the ambient air pollution burden worldwide, causing a range of adverse health effects in exposed populations. The toxicity of woodsmoke, a complex mixture of gases, v...

    Authors: Aiman Abzhanova, Jon Berntsen, Edward R. Pennington, Lisa Dailey, Syed Masood, Ingrid George, Nina Warren, Joseph Martin, Michael D. Hays, Andrew J. Ghio, Jason P. Weinstein, Yong Ho Kim, Earl Puckett and James M. Samet
    Citation: Particle and Fibre Toxicology 2024 21:14
  3. With rapid increase in the global use of various plastics, microplastics (MPs) and nanoplastics (NPs) pollution and their adverse health effects have attracted global attention. MPs have been detected out in h...

    Authors: Shukun Wan, Xiaoqing Wang, Weina Chen, Manli Wang, Jingsong Zhao, Zhongyan Xu, Rong Wang, Chenyang Mi, Zhaodian Zheng and Huidong Zhang
    Citation: Particle and Fibre Toxicology 2024 21:13
  4. Chronic inflammation and fibrosis are characteristics of silicosis, and the inflammatory mediators involved in silicosis have not been fully elucidated. Recently, macrophage-derived exosomes have been reported...

    Authors: Xiaofeng Qin, Zhiyuan Niu, Hui Chen and Yongbin Hu
    Citation: Particle and Fibre Toxicology 2024 21:12
  5. Authors: Caroline Carlé, Delphine Boucher, Luisa Morelli, Camille Larue, Ekaterina Ovtchinnikova, Louise Battut, Kawthar Boumessid, Melvin Airaud, Muriel Quaranta-Nicaise, Jean-Luc Ravanat, Gilles Dietrich, Sandrine Menard, Gérard Eberl, Nicolas Barnich, Emmanuel Mas, Marie Carriere…
    Citation: Particle and Fibre Toxicology 2024 21:11

    The original article was published in Particle and Fibre Toxicology 2023 20:45

  6. Crystalline silica (cSiO2) is a mineral found in rocks; workers from the construction or denim industries are particularly exposed to cSiO2 through inhalation. cSiO2 inhalation increases the risk of silicosis and...

    Authors: Laura Morin, Valérie Lecureur and Alain Lescoat
    Citation: Particle and Fibre Toxicology 2024 21:10
  7. Zinc oxide nanoparticles (ZnONPs) are common materials used in skin-related cosmetics and sunscreen products due to their whitening and strong UV light absorption properties. Although the protective effects of...

    Authors: Bour-Jr Wang, Yu-Ying Chen, Hui-Hsuan Chang, Rong-Jane Chen, Ying-Jan Wang and Yu-Hsuan Lee
    Citation: Particle and Fibre Toxicology 2024 21:9
  8. Inhalation of airborne particulate matter, such as silica and diesel exhaust particles, poses serious long-term respiratory and systemic health risks. Silica exposure can lead to silicosis and systemic autoimm...

    Authors: Lisa MF Janssen, Frauke Lemaire, Nora Fopke Marain, Steven Ronsmans, Natasja Heylen, Arno Vanstapel, Greetje Vande Velde, Jeroen AJ Vanoirbeek, Kenneth Michael Pollard, Manosij Ghosh and Peter HM Hoet
    Citation: Particle and Fibre Toxicology 2024 21:8
  9. Airborne environmental and engineered nanoparticles (NPs) are inhaled and deposited in the respiratory system. The inhaled dose of such NPs and their deposition location in the lung determines their impact on ...

    Authors: Denisa Lizonova, Amogh Nagarkar, Philip Demokritou and Georgios A. Kelesidis
    Citation: Particle and Fibre Toxicology 2024 21:7
  10. Air pollution is recognized as an emerging environmental risk factor for neurological diseases. Large-scale epidemiological studies associate traffic-related particulate matter (PM) with impaired cognitive fun...

    Authors: Henna Jäntti, Steffi Jonk, Mireia Gómez Budia, Sohvi Ohtonen, Ilkka Fagerlund, Mohammad Feroze Fazaludeen, Päivi Aakko-Saksa, Alice Pebay, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Pasi I. Jalava, Tarja Malm and Paula Korhonen
    Citation: Particle and Fibre Toxicology 2024 21:6
  11. Currently, society and industry generate huge amounts of plastics worldwide. The ubiquity of microplastics is obvious, but its impact on the animal and human organism remains not fully understood. The digestiv...

    Authors: Ismena Gałęcka, Natalia Szyryńska and Jarosław Całka
    Citation: Particle and Fibre Toxicology 2024 21:5
  12. Micro- and nanoplastics (MNPs) represent one of the most widespread environmental pollutants of the twenty-first century to which all humans are orally exposed. Upon ingestion, MNPs pass harsh biochemical cond...

    Authors: Hugo Brouwer, Mojtaba Porbahaie, Sjef Boeren, Mathias Busch and Hans Bouwmeester
    Citation: Particle and Fibre Toxicology 2024 21:4
  13. Malignant mesothelioma is an aggressive cancer that often originates in the pleural and peritoneal mesothelium. Exposure to asbestos is a frequent cause. However, studies in rodents have shown that certain mul...

    Authors: Stella Marie Reamon-Buettner, Susanne Rittinghausen, Annika Klauke, Andreas Hiemisch and Christina Ziemann
    Citation: Particle and Fibre Toxicology 2024 21:3
  14. Recent studies showed the presence of microplastic in human lungs. There remains an unmet need to identify the biodistribution of microplastic after inhalation. In this study, we traced the biodistribution of ...

    Authors: Joycie Shanmugiah, Javeria Zaheer, Changkeun Im, Choong Mo Kang and Jin Su Kim
    Citation: Particle and Fibre Toxicology 2024 21:2
  15. As the demand and application of engineered nanomaterials have increased, their potential toxicity to the central nervous system has drawn increasing attention. Tunneling nanotubes (TNTs) are novel cell–cell c...

    Authors: Xinpei Lin, Wei Wang, Xiangyu Chang, Cheng Chen, Zhenkun Guo, Guangxia Yu, Wenya Shao, Siying Wu, Qunwei Zhang, Fuli Zheng and Huangyuan Li
    Citation: Particle and Fibre Toxicology 2024 21:1
  16. The association between air pollution and retinal diseases such as age-related macular degeneration (AMD) has been demonstrated, but the pathogenic correlation is unknown. Damage to the outer blood–retinal bar...

    Authors: Yuzhou Gu, Feiyin Sheng, Mengqin Gao, Li Zhang, Shengjie Hao, Shuying Chen, Rongrong Chen, Yili Xu, Di Wu, Yu Han, Lu Chen, Ye Liu, Bing Lu, Wei Zhao, Xiaoming Lou, Zhijian Chen…
    Citation: Particle and Fibre Toxicology 2023 20:50
  17. Nanoplastics (NPs) are omnipresent in our lives as a new type of pollution with a tiny size. It can enter organisms from the environment, accumulate in the body, and be passed down the food chain. Inflammatory...

    Authors: Juan Ma, Yin Wan, Lingmin Song, Luchen Wang, Huimei Wang, Yingzhi Li and Danfei Huang
    Citation: Particle and Fibre Toxicology 2023 20:49
  18. Extensive production and usage of commercially available products containing TiO2 NPs have led to accumulation in the human body. The deposition of TiO2 NPs has even been detected in the human placenta, which rai...

    Authors: Xianjie Li, Yinger Luo, Di Ji, Zhuyi Zhang, Shili Luo, Ya Ma, Wulan Cao, Chunwei Cao, Phei Er Saw, Hui Chen and Yanhong Wei
    Citation: Particle and Fibre Toxicology 2023 20:48
  19. Diesel exhaust (DE) induces neutrophilia and lymphocytosis in experimentally exposed humans. These responses occur in parallel to nuclear migration of NF-κB and c-Jun, activation of mitogen activated protein k...

    Authors: M. Friberg, A. F. Behndig, J. A. Bosson, Ala Muala, S. Barath, R. Dove, D. Glencross, F. J. Kelly, A. Blomberg, I. S. Mudway, T. Sandström and J. Pourazar
    Citation: Particle and Fibre Toxicology 2023 20:47
  20. Nanoplastics (NPs) could be released into environment through the degradation of plastic products, and their content in the air cannot be ignored. To date, no studies have focused on the cardiac injury effects...

    Authors: Tianyi Zhang, Sheng Yang, Yiling Ge, Xin Wan, Yuxin Zhu, Fei Yang, Jie Li, Saisai Gong, Yanping Cheng, Chengyu Hu, Zaozao Chen, Lihong Yin, Yuepu Pu and Geyu Liang
    Citation: Particle and Fibre Toxicology 2023 20:46
  21. Perinatal exposure to titanium dioxide (TiO2), as a foodborne particle, may influence the intestinal barrier function and the susceptibility to develop inflammatory bowel diseases (IBD) later in life. Here, we in...

    Authors: Caroline Carlé, Delphine Boucher, Luisa Morelli, Camille Larue, Ekaterina Ovtchinnikova, Louise Battut, Kawthar Boumessid, Melvin Airaud, Muriel Quaranta-Nicaise, Jean-Luc Ravanat, Gilles Dietrich, Sandrine Menard, Gérard Eberl, Nicolas Barnich, Emmanuel Mas, Marie Carriere…
    Citation: Particle and Fibre Toxicology 2023 20:45

    The Correction to this article has been published in Particle and Fibre Toxicology 2024 21:11

  22. Microplastics and nanoplastics (MNPs) are emerging environmental contaminants detected in human samples, and have raised concerns regarding their potential risks to human health, particularly neurotoxicity. Th...

    Authors: Yuji Huang, Boxuan Liang, Zhiming Li, Yizhou Zhong, Bo Wang, Bingli Zhang, Jiaxin Du, Rongyi Ye, Hongyi Xian, Weicui Min, Xiliang Yan, Yanhong Deng, Yu Feng, Ruobing Bai, Bingchi Fan, Xingfen Yang…
    Citation: Particle and Fibre Toxicology 2023 20:44
  23. Metallic nanoparticles (NPs) are widely used as food additives for human consumption. NPs reach the bloodstream given their small size, getting in contact with all body organs and cells. NPs have adverse effec...

    Authors: Manuel Alejandro Herrera-Rodríguez, María del Pilar Ramos-Godinez, Agustina Cano-Martínez, Francisco Correa Segura, Angélica Ruiz-Ramírez, Natalia Pavón, Elizabeth Lira-Silva, Rocío Bautista-Pérez, Rosina Sánchez Thomas, Norma Laura Delgado-Buenrostro, Yolanda Irasema Chirino and Rebeca López-Marure
    Citation: Particle and Fibre Toxicology 2023 20:43
  24. Quantifying the dose and distribution of tobacco smoke in the respiratory system is critical for understanding its toxicity, addiction potential, and health impacts. Epidemiologic studies indicate that the inc...

    Authors: Kaisen Lin, Christopher Wallis, Emily M. Wong, Patricia Edwards, Austin Cole, Laura Van Winkle and Anthony S. Wexler
    Citation: Particle and Fibre Toxicology 2023 20:42
  25. Epidemiological studies have demonstrated that individuals with preexisting conditions, including diabetes mellitus (DM), are more susceptible to air pollution. However, the underlying mechanisms remain unclea...

    Authors: Yiqun Mo, Luke Mo, Yue Zhang, Yuanbao Zhang, Jiali Yuan and Qunwei Zhang
    Citation: Particle and Fibre Toxicology 2023 20:41
  26. The understanding of inhaled particle respiratory tract deposition is a key link to understand the health effects of particles or the efficiency for medical drug delivery via the lung. However, there are few e...

    Authors: Jenny Rissler, Madeleine Peterson Sjögren, Julia Linell, Amalia Larsson Hurtig, Per Wollmer and Jakob Löndahl
    Citation: Particle and Fibre Toxicology 2023 20:40
  27. Epidemiological studies have related desert dust events to increased respiratory morbidity and mortality. Although the Sahara is the largest source of desert dust, Saharan dust (SD) has been barely examined in...

    Authors: Gerrit Bredeck, Jochen Dobner, Burkhard Stahlmecke, Khanneh Wadinga Fomba, Hartmut Herrmann, Andrea Rossi and Roel P. F. Schins
    Citation: Particle and Fibre Toxicology 2023 20:39
  28. Recently, mesoporous nanomaterials with widespread applications have attracted great interest in the field of drug delivery due to their unique structure and good physiochemical properties. As a biomimetic nan...

    Authors: Bang-Yao Chen, Si-Ying Hong, Han-Min Wang, Yi Shi, Peng Wang, Xiao-Juan Wang, Qian-Yang Jiang, Ke-Da Yang, Wei Chen and Xiao-Ling Xu
    Citation: Particle and Fibre Toxicology 2023 20:38
  29. Carbon fibers are high aspect ratio structures with diameters on the submicron scale. Vapor grown carbon fibers are contained within multi-walled carbon tubes, with VGCFâ„¢-H commonly applied as a conductive add...

    Authors: Kei Sato, Hiroko Fukui, Yuji Hagiwara, Ryoji Ogawa, Ayako Nishioka, Takamasa Numano, Taiki Sugiyama, Mayumi Kawabe, Yukinori Mera and Tadashi Yoneda
    Citation: Particle and Fibre Toxicology 2023 20:37
  30. Limbal stem/progenitor cells (LSPCs) play a crucial role in maintaining corneal health by regulating epithelial homeostasis. Although PM2.5 is associated with the occurrence of several corneal diseases, its ef...

    Authors: Shengjie Hao, Zhijian Chen, Yuzhou Gu, Lu Chen, Feiyin Sheng, Yili Xu, Di Wu, Yu Han, Bing Lu, Shuying Chen, Wei Zhao, Houfa Yin, Xiaofeng Wang, S. Amer Riazuddin, Xiaoming Lou, Qiuli Fu…
    Citation: Particle and Fibre Toxicology 2023 20:36
  31. With the large-scale production and application of amorphous silica nanoparticles (aSiNPs), its adverse health effects are more worthy of our attention. Our previous research has demonstrated for the first tim...

    Authors: Liyan Xiao, Jinyan Pang, Hua Qin, Liyang Dou, Man Yang, Ji Wang, Xianqing Zhou, Yang Li, Junchao Duan and Zhiwei Sun
    Citation: Particle and Fibre Toxicology 2023 20:34
  32. Nanodiamonds (NDs) have gained a rapidly growing interest in biomedical applications; however, little is known regarding their biokinetics owing to difficulties in measurements and limited synthesis/purificati...

    Authors: Jiyoung Jeong, Soyeon Jeon, Songyeon Kim, Sinuk Lee, Gyuri Kim, Eunsol Bae, Yeonjeong Ha, Seung Whan Lee, Ji-Su Kim, Dong-Jae Kim and Wan-Seob Cho
    Citation: Particle and Fibre Toxicology 2023 20:33
  33. Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) has been reported to exert strong pro-inflammatory and pro-fibrotic adjuvant effects in mouse models of allergic lung disease. However, the molecula...

    Authors: Ho Young Lee, Dorothy J. You, Alexia Taylor-Just, Logan J. Tisch, Ryan D. Bartone, Hannah M. Atkins, Lauren M. Ralph, Silvio Antoniak and James C. Bonner
    Citation: Particle and Fibre Toxicology 2023 20:32
  34. Traffic-derived particles are important contributors to the adverse health effects of ambient particulate matter (PM). In Nordic countries, mineral particles from road pavement and diesel exhaust particles (DE...

    Authors: Magne Refsnes, Tonje Skuland, Rikke Jørgensen, Vegard Sæter-Grytting, Brynhild Snilsberg, Johan Øvrevik, Jørn A. Holme and Marit Låg
    Citation: Particle and Fibre Toxicology 2023 20:31
  35. Exposure to wood smoke has been shown to contribute to adverse respiratory health effects including airway infections, but the underlying mechanisms are unclear. A preceding study failed to confirm any acute i...

    Authors: Alva Hansson, Gregory Rankin, Oskari Uski, Maria Friberg, Jamshid Pourazar, Robert Lindgren, Natxo García-López, Christoffer Boman, Thomas Sandström, Annelie Behndig and Ala Muala
    Citation: Particle and Fibre Toxicology 2023 20:30
  36. Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools. Epithelial mesenchymal transi...

    Authors: Shaoqi Yang, Yuheng Sun, Min Long, Xinbei Zhou, Mengqin Yuan, Liliang Yang, Wei Luo, Yusi Cheng, Xinxin Zhang, Wei Jiang and Jie Chao
    Citation: Particle and Fibre Toxicology 2023 20:29
  37. Exposure to particulate matter (PM) with an aerodynamic diameter less than 2.5 Î¼m (PM2.5) is a risk factor for developing pulmonary diseases and the worsening of ongoing disease. Mitochondrial fission and fusion ...

    Authors: Qi Liu, Jiali Weng, Chenfei Li, Yi Feng, Meiqin Xie, Xiaohui Wang, Qing Chang, Mengnan Li, Kian Fan Chung, Ian M Adcock, Yan Huang, Hai Zhang and Feng Li
    Citation: Particle and Fibre Toxicology 2023 20:28
  38. Edible gold (Au) is commonly used as a food additive (E175 in EU) for confectionery and cake decorations, coatings and in beverages. Food-grade gold is most often composed of thin Au sheets or flakes exhibitin...

    Authors: Lauris Evariste, Bruno Lamas, Sandrine Ellero-Simatos, Laure Khoury, Christel Cartier, Eric Gaultier, Benoit Chassaing, Nicolas Feltin, Laurent Devoille, Georges Favre, Marc Audebert and Eric Houdeau
    Citation: Particle and Fibre Toxicology 2023 20:27
  39. There is insufficient knowledge about the systemic health effects of exposure to fine (PM2.5) and ultrafine particles emitted from typical indoor sources, including cooking and candlelight burning. We examined wh...

    Authors: Karin Rosenkilde Laursen, Nichlas Vous Christensen, Frans AA Mulder, Jörg Schullehner, Hans Jürgen Hoffmann, Annie Jensen, Peter Møller, Steffen Loft, Anna-Carin Olin, Berit B. Rasmussen, Bernadette Rosati, Bo Strandberg, Marianne Glasius, Merete Bilde and Torben Sigsgaard
    Citation: Particle and Fibre Toxicology 2023 20:26
  40. We previously found that air pollution particles reaching the gastrointestinal tract elicit gut inflammation as shown by up-regulated gene expression of pro-inflammatory cytokines and monocyte/macrophage marke...

    Authors: Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Zora Baumann, Neena Parayil, Faiza Noreen, Julien Roux, Daniel T. Meier and Claudia Cavelti-Weder
    Citation: Particle and Fibre Toxicology 2023 20:25
  41. Titanium dioxide (TiO2), no matter in nanoscale or micron sizes, has been widely used in food industry as additives for decades. Given the potential impact of TiO2 on the gastrointestinal epithelial and parenchym...

    Authors: Shumin Duan, Hongbo Wang, Yanjun Gao, Xiang Wang, Lizhi Lyu and Yun Wang
    Citation: Particle and Fibre Toxicology 2023 20:24
  42. Though titanium dioxide (TiO2) is generally considered to have a low impact in the human body, the safety of TiO2 containing nanosized particles (NPs) has attracted attention. We found that the toxicity of silver...

    Authors: Jun-ichi Akagi, Yasuko Mizuta, Hirotoshi Akane, Takeshi Toyoda and Kumiko Ogawa
    Citation: Particle and Fibre Toxicology 2023 20:23
  43. Copper oxide nanoparticles (Nano-CuO) are one of the most produced and used nanomaterials. Previous studies have shown that exposure to Nano-CuO caused acute lung injury, inflammation, and fibrosis. However, t...

    Authors: Yuanbao Zhang, Yiqun Mo, Yue Zhang, Jiali Yuan and Qunwei Zhang
    Citation: Particle and Fibre Toxicology 2023 20:22
  44. The widespread use of new engineered nanomaterials (ENMs) in industries such as cosmetics, electronics, and diagnostic nanodevices, has been revolutionizing our society. However, emerging studies suggest that ...

    Authors: João Meneses, Michael González-Durruthy, Eli Fernandez-de-Gortari, Alla P. Toropova, Andrey A. Toropov and Ernesto Alfaro-Moreno
    Citation: Particle and Fibre Toxicology 2023 20:21
  45. Airborne pollution particles have been shown to translocate from the mother’s lung to the fetal circulation, but their distribution and internal placental-fetal tissue load remain poorly explored. Here, we inv...

    Authors: Eva Bongaerts, Tim S Nawrot, Congrong Wang, Marcel Ameloot, Hannelore Bové, Maarten BJ Roeffaers, Pascale Chavatte-Palmer, Anne Couturier-Tarrade and Flemming R Cassee
    Citation: Particle and Fibre Toxicology 2023 20:20
  46. Asbestos is a fibrous mineral that was widely used in the past. However, asbestos inhalation is associated with an aggressive type of cancer known as malignant mesothelioma (MM). After inhalation, an iron-rich...

    Authors: Maya-Liliana Avramescu, Christian Potiszil, Tak Kunihiro, Kazunori Okabe and Eizo Nakamura
    Citation: Particle and Fibre Toxicology 2023 20:19
  47. Prussian blue (PB) nanoparticles (NPs) have been intensively investigated for medical applications, but an in-depth toxicological investigation of PB NPs has not been implemented. In the present study, a compr...

    Authors: Haijing Qu, Xing Jin, Wei Cheng, Dongqi Wu, Boyu Ma, Chenmei Lou, Jian Zheng, Lijia Jing, Xiangdong Xue and Yang Wang
    Citation: Particle and Fibre Toxicology 2023 20:18
  48. Inhalation is a portal-of-entry for aerosols via the respiratory tract where particulate burden accumulates depending on sites of particle deposition, normal clearance mechanisms, and particle solubility. The ...

    Authors: James S. Brown and Gary L. Diamond
    Citation: Particle and Fibre Toxicology 2023 20:17
  49. Exposure to micro- and nanoplastic particles (MNPs) in humans is being identified in both the indoor and outdoor environment. Detection of these materials in the air has made inhalation exposure to MNPs a majo...

    Authors: Chelsea M Cary, Talia N Seymore, Dilpreet Singh, Kinal N Vayas, Michael J Goedken, Samantha Adams, Marianne Polunas, Vasanthi R Sunil, Debra L Laskin, Philip Demokritou and Phoebe A Stapleton
    Citation: Particle and Fibre Toxicology 2023 20:16

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