Skip to main content

Articles

Page 10 of 13

  1. Particulate air pollution has been linked to an increased risk of cardiovascular disease and cancer. Animal studies have shown that inhalation of air particulates induces mutations in the male germline. Expand...

    Authors: Anne Mette Zenner Boisen, Thomas Shipley, Petra Jackson, Karin Sørig Hougaard, Håkan Wallin, Carole L Yauk and Ulla Vogel

    Citation: Particle and Fibre Toxicology 2012 9:19

    Content type: Short report

    Published on:

  2. Titanium dioxide (TiO2) nanoparticles (NPs) are widely used due to their specific properties, like UV filters in sunscreen. In that particular case TiO2 NPs are surface modified to avoid photocatalytic effects. T...

    Authors: Matthieu Fisichella, Frederic Berenguer, Gerard Steinmetz, Melanie Auffan, Jerome Rose and Odette Prat

    Citation: Particle and Fibre Toxicology 2012 9:18

    Content type: Research

    Published on:

  3. Increasing concern has been expressed regarding the potential adverse health effects that may be associated with human exposure to inhaled multi-walled carbon nanotubes (MWCNTs). Thus it is imperative that an ...

    Authors: Michael Gasser, Peter Wick, Martin JD Clift, Fabian Blank, Liliane Diener, Bing Yan, Peter Gehr, Harald F Krug and Barbara Rothen-Rutishauser

    Citation: Particle and Fibre Toxicology 2012 9:17

    Content type: Research

    Published on:

  4. Single-walled carbon nanotubes (SWCNT) trigger pronounced inflammation and fibrosis in the lungs of mice following administration via pharyngeal aspiration or inhalation. Human exposure to SWCNT in an occupati...

    Authors: Linda Swedin, Romanico Arrighi, Britta Andersson-Willman, Ashley Murray, Yunying Chen, Mikael C I Karlsson, Susanna Kumlien Georén, Alexey V Tkach, Anna A Shvedova, Bengt Fadeel, Antonio Barragan and Annika Scheynius

    Citation: Particle and Fibre Toxicology 2012 9:16

    Content type: Research

    Published on:

  5. We determined the ability of a model nanoparticle (NP) (titanium dioxide, TiO2) to modulate sensitization induced by a known potent dermal sensitizer (dinitrochlorobenzene) using a variant of the local lymph node...

    Authors: Salik Hussain, Stijn Smulders, Vanessa De Vooght, Bert Ectors, Sonja Boland, Francelyne Marano, Kirsten L Van Landuyt, Benoit Nemery, Peter HM Hoet and Jeroen AJ Vanoirbeek

    Citation: Particle and Fibre Toxicology 2012 9:15

    Content type: Research

    Published on:

  6. Carbon nanotubes (CNTs) are engineered graphene cylinders with numerous applications in engineering, electronics and medicine. However, CNTs cause inflammation and fibrosis in the rodent lung, suggesting a pot...

    Authors: Jong Kwon Lee, Brian C Sayers, Kyung-Soo Chun, Huei-Chen Lao, Jeanette K Shipley-Phillips, James C Bonner and Robert Langenbach

    Citation: Particle and Fibre Toxicology 2012 9:14

    Content type: Research

    Published on:

  7. Particle toxicology arose in order to understand the mechanisms of adverse effects of 3 major particle types that had historically exerted the greatest toll of ill-health—quartz, coal and asbestos. By the midd...

    Authors: Ken Donaldson and Anthony Seaton

    Citation: Particle and Fibre Toxicology 2012 9:13

    Content type: Review

    Published on:

  8. There is growing evidence that particulate air pollution derived from wood stoves causes acute inflammation in the respiratory system, increases the incidence of asthma and other allergic diseases, and increas...

    Authors: Ingunn Skogstad Riddervold, Jakob Hjort Bønløkke, Anna-Carin Olin, Therese Koops Grønborg, Vivi Schlünssen, Kristin Skogstrand, David Hougaard, Andreas Massling and Torben Sigsgaard

    Citation: Particle and Fibre Toxicology 2012 9:12

    Content type: Research

    Published on:

  9. Polymer nanoparticles (PNP) are becoming increasingly important in nanomedicine and food-based applications. Size and surface characteristics are often considered to be important factors in the cellular intera...

    Authors: Sourav Bhattacharjee, Dmitry Ershov, Kleanthis Fytianos, Jasper van der Gucht, Gerrit M Alink, Ivonne M C M Rietjens, Antonius T M Marcelis and Han Zuilhof

    Citation: Particle and Fibre Toxicology 2012 9:11

    Content type: Research

    Published on:

  10. Carbon nanotubes (CNT) and carbon nanofibers (CNF) are allotropes of carbon featuring fibrous morphology. The dimensions and high aspect ratio of CNT and CNF have prompted the comparison with naturally occurri...

    Authors: Ashley R Murray, Elena R Kisin, Alexey V Tkach, Naveena Yanamala, Robert Mercer, Shih-Houng Young, Bengt Fadeel, Valerian E Kagan and Anna A Shvedova

    Citation: Particle and Fibre Toxicology 2012 9:10

    Content type: Research

    Published on:

  11. Inhalation of diesel exhaust impairs vascular function in man, by a mechanism that has yet to be fully established. We hypothesised that pulmonary exposure to diesel exhaust particles (DEP) would cause endothe...

    Authors: Sarah Robertson, Gillian A Gray, Rodger Duffin, Steven G McLean, Catherine A Shaw, Patrick WF Hadoke, David E Newby and Mark R Miller

    Citation: Particle and Fibre Toxicology 2012 9:9

    Content type: Research

    Published on:

  12. Carbon nanotubes (CNT) are high aspect ratio nanoparticles with diameters in the nanometre range but lengths extending up to hundreds of microns. The structural similarities between CNT and asbestos have raise...

    Authors: Fiona A Murphy, Anja Schinwald, Craig A Poland and Ken Donaldson

    Citation: Particle and Fibre Toxicology 2012 9:8

    Content type: Research

    Published on:

  13. Exposure to wood smoke is associated with respiratory symptoms, whereas knowledge on systemic effects is limited. We investigated effects on systemic inflammation, oxidative stress and microvascular function (...

    Authors: Lykke Forchhammer, Peter Møller, Ingunn Skogstad Riddervold, Jakob Bønløkke, Andreas Massling, Torben Sigsgaard and Steffen Loft

    Citation: Particle and Fibre Toxicology 2012 9:7

    Content type: Research

    Published on:

  14. Exposure to respirable crystalline silica particles, as opposed to amorphous silica, is associated with lung inflammation, pulmonary fibrosis (silicosis), and potentially with lung cancer. We used Affymetrix/G...

    Authors: Timothy N Perkins, Arti Shukla, Paul M Peeters, Jeremy L Steinbacher, Christopher C Landry, Sherrill A Lathrop, Chad Steele, Niki L Reynaert, Emiel FM Wouters and Brooke T Mossman

    Citation: Particle and Fibre Toxicology 2012 9:6

    Content type: Research

    Published on:

  15. Widespread occupational exposure to carbon black nanoparticles (CBNPs) raises concerns over their safety. CBNPs are genotoxic in vitro but less is known about their genotoxicity in various organs in vivo.

    Authors: Julie A Bourdon, Anne T Saber, Nicklas R Jacobsen, Keld A Jensen, Anne M Madsen, Jacob S Lamson, Håkan Wallin, Peter Møller, Steffen Loft, Carole L Yauk and Ulla B Vogel

    Citation: Particle and Fibre Toxicology 2012 9:5

    Content type: Research

    Published on:

  16. Little is known of how the toxicity of nanoparticles is affected by the incorporation in complex matrices. We compared the toxic effects of the titanium dioxide nanoparticle UV-Titan L181 (NanoTiO2), pure or embe...

    Authors: Anne Thoustrup Saber, Nicklas Raun Jacobsen, Alicia Mortensen, Józef Szarek, Petra Jackson, Anne Mette Madsen, Keld Alstrup Jensen, Ismo K Koponen, Gunnar Brunborg, Kristine Bjerve Gützkow, Ulla Vogel and Håkan Wallin

    Citation: Particle and Fibre Toxicology 2012 9:4

    Content type: Research

    Published on:

  17. Due to the rising use of nanomaterials (NMs), there is concern that NMs induce undesirable biological effects because of their unique physicochemical properties. Recently, we reported that amorphous silica nan...

    Authors: Toshiro Hirai, Tomoaki Yoshikawa, Hiromi Nabeshi, Tokuyuki Yoshida, Saeko Tochigi, Ko-ichi Ichihashi, Miyuki Uji, Takanori Akase, Kazuya Nagano, Yasuhiro Abe, Haruhiko Kamada, Norio Itoh, Shin-ichi Tsunoda, Yasuo Yoshioka and Yasuo Tsutsumi

    Citation: Particle and Fibre Toxicology 2012 9:3

    Content type: Research

    Published on:

  18. Histamine released from mast cells, through complex interactions involving the binding of IgE to FcεRI receptors and the subsequent intracellular Ca2+ signaling, can mediate many allergic/inflammatory responses. ...

    Authors: Eric Y Chen, Maria Garnica, Yung-Chen Wang, Alexander J Mintz, Chi-Shuo Chen and Wei-Chun Chin

    Citation: Particle and Fibre Toxicology 2012 9:2

    Content type: Research

    Published on:

  19. Recently, we used cell-free assays to demonstrate the toxic effects of complex mixtures of organic extracts from urban air particles (PM2.5) collected in four localities of the Czech Republic (Ostrava-Bartovic...

    Authors: Helena Líbalová, Kateřina Uhlířová, Jiří Kléma, Miroslav Machala, Radim J Šrám, Miroslav Ciganek and Jan Topinka

    Citation: Particle and Fibre Toxicology 2012 9:1

    Content type: Research

    Published on:

  20. In nanotoxicology, the exact role of particle shape, in relation to the composition, on the capacity to induce toxicity is largely unknown. We investigated the toxic and immunotoxic effects of silver wires (le...

    Authors: Linda C Stoehr, Edgar Gonzalez, Andreas Stampfl, Eudald Casals, Albert Duschl, Victor Puntes and Gertie J Oostingh

    Citation: Particle and Fibre Toxicology 2011 8:36

    Content type: Research

    Published on:

  21. Our previous studies demonstrated that tilmicosin-loaded hydrogenated castor oil solid lipid nanoparticles (Til-HCO-SLN) are a promising formulation for enhanced pharmacological activity and therapeutic effica...

    Authors: Shuyu Xie, Fenghua Wang, Yan Wang, Luyan Zhu, Zhao Dong, Xiaofang Wang, Xihe Li and WenZhong Zhou

    Citation: Particle and Fibre Toxicology 2011 8:33

    Content type: Research

    Published on:

  22. There is growing evidence that exposure to small size particulate matter increases the risk of developing cardiovascular disease.

    Authors: Lone Mikkelsen, Majid Sheykhzade, Keld A Jensen, Anne T Saber, Nicklas R Jacobsen, Ulla Vogel, Håkan Wallin, Steffen Loft and Peter Møller

    Citation: Particle and Fibre Toxicology 2011 8:32

    Content type: Research

    Published on:

  23. Inhalation of (nano)particles may lead to pulmonary inflammation. However, the precise mechanisms of particle uptake and generation of inflammatory mediators by alveolar macrophages (AM) are still poorly under...

    Authors: Agnes M Scherbart, Julia Langer, Alexey Bushmelev, Damiёn van Berlo, Petra Haberzettl, Frederik-Jan van Schooten, Annette M Schmidt, Christine R Rose, Roel PF Schins and Catrin Albrecht

    Citation: Particle and Fibre Toxicology 2011 8:31

    Content type: Research

    Published on:

  24. Obesity can be linked to disease risks such as diabetes and cardiovascular disorders, but recently, the adipose tissue (AT) macrophage also emerges as actively participating in inflammation and immune function...

    Authors: Alexander A Götz, Jan Rozman, Heiko G Rödel, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Martin Klingenspor and Tobias Stoeger

    Citation: Particle and Fibre Toxicology 2011 8:30

    Content type: Research

    Published on:

  25. Human exposure to nanoparticles (NPs) and environmental bacteria can occur simultaneously. NPs induce inflammatory responses and oxidative stress but may also have immune-suppressive effects, impairing macroph...

    Authors: Jong Sung Kim, Andrea Adamcakova-Dodd, Patrick T O'Shaughnessy, Vicki H Grassian and Peter S Thorne

    Citation: Particle and Fibre Toxicology 2011 8:29

    Content type: Research

    Published on:

  26. The alveolar macrophage (AM) - first line of innate immune defence against pathogens and environmental irritants - constitutively expresses peroxisome-proliferator activated receptor γ (PPARγ). PPARγ ligand-in...

    Authors: Alexander A Götz, Antonio Vidal-Puig, Heiko G Rödel, Martin Hrabé de Angelis and Tobias Stoeger

    Citation: Particle and Fibre Toxicology 2011 8:28

    Content type: Research

    Published on:

  27. Large production volumes of zinc oxide nanoparticles (ZnONP) might be anticipated to pose risks, of accidental inhalation in occupational and even in consumer settings. Herein, we further investigated the path...

    Authors: Wan-Seob Cho, Rodger Duffin, Sarah EM Howie, Chris J Scotton, William AH Wallace, William MacNee, Mark Bradley, Ian L Megson and Ken Donaldson

    Citation: Particle and Fibre Toxicology 2011 8:27

    Content type: Research

    Published on:

  28. Ambient particulate matter (PM) exposure is associated with respiratory and cardiovascular morbidity and mortality. To what extent such effects are different for PM obtained from different sources or locations...

    Authors: Maaike Steenhof, Ilse Gosens, Maciej Strak, Krystal J Godri, Gerard Hoek, Flemming R Cassee, Ian S Mudway, Frank J Kelly, Roy M Harrison, Erik Lebret, Bert Brunekreef, Nicole AH Janssen and Raymond HH Pieters

    Citation: Particle and Fibre Toxicology 2011 8:26

    Content type: Research

    Published on:

  29. Exposure to ambient air particles matter (PM) has been associated with increased risk of lung cancer. Aberrant tumor suppressor gene promoter methylation has emerged as a promising biomarker for cancers, inclu...

    Authors: Lifang Hou, Xiao Zhang, Letizia Tarantini, Francesco Nordio, Matteo Bonzini, Laura Angelici, Barbara Marinelli, Giovanna Rizzo, Laura Cantone, Pietro Apostoli, Pier Alberto Bertazzi and Andrea Baccarelli

    Citation: Particle and Fibre Toxicology 2011 8:25

    Content type: Research

    Published on:

  30. Multi-walled carbon nanotubes (MWCNTs) are widely used in many disciplines due to their unique physical and chemical properties. Therefore, some concerns about the possible human health and environmental impac...

    Authors: Xiaojia Wang, Pranita Katwa, Ramakrishna Podila, Pengyu Chen, Pu Chun Ke, Apparao M Rao, Dianne M Walters, Christopher J Wingard and Jared M Brown

    Citation: Particle and Fibre Toxicology 2011 8:24

    Content type: Research

    Published on:

  31. Acute exposure to elevated levels of environmental particulate matter (PM) is associated with increasing morbidity and mortality rates. These adverse health effects, e.g. culminating in respiratory and cardiov...

    Authors: Susanne Fritsch-Decker, Tanja Both, Sonja Mülhopt, Hanns-Rudolf Paur, Carsten Weiss and Silvia Diabaté

    Citation: Particle and Fibre Toxicology 2011 8:23

    Content type: Research

    Published on:

  32. Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be test...

    Authors: Thomas AJ Kuhlbusch, Christof Asbach, Heinz Fissan, Daniel Göhler and Michael Stintz

    Citation: Particle and Fibre Toxicology 2011 8:22

    Content type: Review

    Published on:

  33. Multi-walled carbon nanotubes (MWCNTs) are new manufactured nanomaterials with a wide spectrum of commercial applications. To address the hypothesis that MWCNTs cause persistent pulmonary pathology, C57BL/6J m...

    Authors: Robert R Mercer, Ann F Hubbs, James F Scabilloni, Liying Wang, Lori A Battelli, Sherri Friend, Vincent Castranova and Dale W Porter

    Citation: Particle and Fibre Toxicology 2011 8:21

    Content type: Research

    Published on:

  34. Prior studies have demonstrated a link between air pollution and metabolic diseases such as type II diabetes. Changes in adipose tissue and its mitochondrial content/function are closely associated with the de...

    Authors: Zhaobin Xu, Xiaohua Xu, Mianhua Zhong, Ian P Hotchkiss, Ryan P Lewandowski, James G Wagner, Lori A Bramble, Yifeng Yang, Aixia Wang, Jack R Harkema, Morton Lippmann, Sanjay Rajagopalan, Lung-Chi Chen and Qinghua Sun

    Citation: Particle and Fibre Toxicology 2011 8:20

    Content type: Research

    Published on:

  35. Exposure to particulate matter (PM) air pollution may be an important environmental factor leading to exacerbations of inflammatory illnesses in the GI tract. PM can gain access to the gastrointestinal (GI) tr...

    Authors: Ece A Mutlu, Phillip A Engen, Saul Soberanes, Daniela Urich, Christopher B Forsyth, Recep Nigdelioglu, Sergio E Chiarella, Kathryn A Radigan, Angel Gonzalez, Shriram Jakate, Ali Keshavarzian, GR Scott Budinger and Gökhan M Mutlu

    Citation: Particle and Fibre Toxicology 2011 8:19

    Content type: Research

    Published on:

  36. The study investigated the distribution of silver after 28 days repeated oral administration of silver nanoparticles (AgNPs) and silver acetate (AgAc) to rats. Oral administration is a relevant route of exposu...

    Authors: Katrin Loeschner, Niels Hadrup, Klaus Qvortrup, Agnete Larsen, Xueyun Gao, Ulla Vogel, Alicja Mortensen, Henrik Rye Lam and Erik H Larsen

    Citation: Particle and Fibre Toxicology 2011 8:18

    Content type: Research

    Published on:

  37. The most common causes of granulomatous inflammation are persistent pathogens and poorly-degradable irritating materials. A characteristic pathological reaction to intratracheal instillation, pharyngeal aspira...

    Authors: Vanesa C Sanchez, Paula Weston, Aihui Yan, Robert H Hurt and Agnes B Kane

    Citation: Particle and Fibre Toxicology 2011 8:17

    Content type: Research

    Published on:

  38. Gold nanoparticles are widely used in consumer products, including cosmetics, food packaging, beverages, toothpaste, automobiles, and lubricants. With this increase in consumer products containing gold nanopar...

    Authors: Jae Hyuck Sung, Jun Ho Ji, Jung Duck Park, Moon Yong Song, Kyung Seuk Song, Hyeon Ryol Ryu, Jin Uk Yoon, Ki Soo Jeon, Jayoung Jeong, Beom Seok Han, Yong Hyun Chung, Hee Kyung Chang, Ji Hyun Lee, Dong Won Kim, Bruce J Kelman and Il Je Yu

    Citation: Particle and Fibre Toxicology 2011 8:16

    Content type: Research

    Published on:

  39. It has been suggested that carbon nanotubes might conform to the fibre pathogenicity paradigm that explains the toxicities of asbestos and other fibres on a continuum based on length, aspect ratio and biopersi...

    Authors: Megan J Osmond-McLeod, Craig A Poland, Fiona Murphy, Lynne Waddington, Howard Morris, Stephen C Hawkins, Steve Clark, Rob Aitken, Maxine J McCall and Ken Donaldson

    Citation: Particle and Fibre Toxicology 2011 8:15

    Content type: Research

    Published on:

  40. Authors: Karin S Hougaard, Petra Jackson, Keld A Jensen, Jens J Sloth, Katrin Löschner, Erik H Larsen, Renie K Birkedal, Anni Vibenholt, Anne-Mette Z Boisen, Håkan Wallin and Ulla Vogel

    Citation: Particle and Fibre Toxicology 2011 8:14

    Content type: Erratum

    Published on:

    The original article was published in Particle and Fibre Toxicology 2010 7:16

  41. Inhalation of fine particulate matter (<2.5 μm; fine PM) has been shown to increase the risk for cardiovascular events. In this letter, we reappraise the role of tissue factor (TF) antigen and we also summariz...

    Authors: Evren Kilinç, Holger Schulz, Gerhardus JAJM Kuiper, Henri MH Spronk, Hugo ten Cate, Swapna Upadhyay, Koustav Ganguly, Tobias Stoeger, Manuela Semmler-Bhenke, Shinji Takenaka, Wolfgang G Kreyling, Mike Pitz, Peter Reitmeir, Annette Peters, Oliver Eickelberg and H Erich Wichmann

    Citation: Particle and Fibre Toxicology 2011 8:12

    Content type: Letter to the Editor

    Published on:

  42. Increased asthma risk/exacerbation in children and infants is associated with exposure to elevated levels of ultrafine particulate matter (PM). The presence of a newly realized class of pollutants, environment...

    Authors: Shrilatha Balakrishna, Jordy Saravia, Paul Thevenot, Terry Ahlert, Slawo Lominiki, Barry Dellinger and Stephania A Cormier

    Citation: Particle and Fibre Toxicology 2011 8:11

    Content type: Research

    Published on:

  43. Some manufactured nanoparticles are metal-based and have a wide variety of applications in electronic, engineering and medicine. Until now, many studies have described the potential toxicity of NPs on pulmonar...

    Authors: Igor Pujalté, Isabelle Passagne, Brigitte Brouillaud, Mona Tréguer, Etienne Durand, Céline Ohayon-Courtès and Béatrice L'Azou

    Citation: Particle and Fibre Toxicology 2011 8:10

    Content type: Research

    Published on:

  44. Engineered nanomaterials display unique properties that may have impact on human health, and thus require a reliable evaluation of their potential toxicity. Here, we performed a standardized in vitro screening of...

    Authors: Alexandra Kroll, Christian Dierker, Christina Rommel, Daniela Hahn, Wendel Wohlleben, Christian Schulze-Isfort, Christian Göbbert, Matthias Voetz, Ferdinand Hardinghaus and Jürgen Schnekenburger

    Citation: Particle and Fibre Toxicology 2011 8:9

    Content type: Research

    Published on:

  45. With the increasing use of nanomaterials, the need for methods and assays to examine their immunosafety is becoming urgent, in particular for nanomaterials that are deliberately administered to human subjects ...

    Authors: Gertie J Oostingh, Eudald Casals, Paola Italiani, Renato Colognato, René Stritzinger, Jessica Ponti, Tobias Pfaller, Yvonne Kohl, Daniëlla Ooms, Flavia Favilli, Hilde Leppens, Davide Lucchesi, François Rossi, Inge Nelissen, Hagen Thielecke, Victor F Puntes…

    Citation: Particle and Fibre Toxicology 2011 8:8

    Content type: Methodology

    Published on:

  46. Occupational or environmental exposure to asbestos fibres is associated with pleural and parenchymal lung diseases. A histopathologic hallmark of exposure to asbestos is the presence in lung parenchyma of the ...

    Authors: Lorella Pascolo, Alessandra Gianoncelli, Burkhard Kaulich, Clara Rizzardi, Manuela Schneider, Cristina Bottin, Maurizio Polentarutti, Maya Kiskinova, Antonio Longoni and Mauro Melato

    Citation: Particle and Fibre Toxicology 2011 8:7

    Content type: Research

    Published on:

  47. To date silica nanoparticles (SNPs) play an important role in modern technology and nanomedicine. SNPs are present in various materials (tyres, electrical and thermal insulation material, photovoltaic faciliti...

    Authors: Jennifer Kasper, Maria I Hermanns, Christoph Bantz, Michael Maskos, Roland Stauber, Christine Pohl, Ronald E Unger and James C Kirkpatrick

    Citation: Particle and Fibre Toxicology 2011 8:6

    Content type: Research

    Published on:

Annual Journal Metrics